cooley's anaemia

Thân thiện

A young child with Cooley's anaemia receives a blood transfusion in a hospital.

Definition

1. Noun:
   • A severe inherited blood disorder: Cooley's anaemia is a fatal form of homozygous thalassemia, inherited from both parents, characterized by the absence or severe deficiency of normal hemoglobin.
   • A condition with specific physical manifestations: The disease involves skeletal deformities and the enlargement of organs such as the heart, spleen, and liver.

Usage Examples

• Noun:
  • The child was diagnosed with Cooley's anaemia, requiring regular blood transfusions.
  • Research into gene therapy offers hope for a future cure for Cooley's anaemia.

Advanced Usage

• Medical terminology: In clinical contexts, "Cooley's anaemia" is often used synonymously with "beta-thalassemia major" to describe the most severe form of the genetic disorder.
  • The treatment plan for Cooley's anaemia is complex and lifelong.

Variants and Related Words

• Cooley's anemia (n): The American English spelling variant, using 'anemia'.
• Thalassemia major (n): A more general medical term often used interchangeably with Cooley's anaemia.
• Beta-thalassemia major (n): The specific genetic designation for this condition.

Synonyms

• Beta-thalassemia major: The formal medical term.
• Mediterranean anemia: An older, less precise term referencing the disease's prevalence in certain regions.

Related Phrases

• To be treated for Cooley's anaemia: To undergo medical management for the condition.
  • The patient has been treated for Cooley's anaemia since infancy.

Học thuật

Noun

1. a fatal form of homozygous thalassemia (inherited from both parents) in which there is no hemoglobin; skeletal deformations; heart and spleen and liver enlarged

Từ đồng nghĩa

• Cooley's anemia
• Cooley's anaemia
• thalassemia major
• thalassaemia major